Certianly not her current donor base. She might qualify for public financing after the fact, but I'm thinking that even if she were willing to abandon the Democratic party and try it, she and Bill aren't risking their personal fortune and political legacy on it. Perot was (and is) a billionaire and could afford to finance his own campaign, not so for the Clintons. Not to mention she'd have to crawl back to the Democrats in a couple years if she wanted her senate seat back.

Bet on her being the next majority leader. She's earned a leadership position in the party, and they'll give her one. Thats the deal they'll strike.